Irisin as a Potential Biomarker Associated with Myocardial Injuries in Patients with Severe Hypothyroidism

Table 4

Multivariate linear regression for the association of serum irisin levels with native T1 values in severe hypothyroidism patients.

Univariate linear regression			Multivariate linear regression^♆			Multivariate linear regression^☧			value
Variables	β	95% CI	value	β	95% CI	value	β	95% CI
Age	−0.886	−4.880 to 3.108	0.651	0.319	−3.494 to 4.131	0.864	−1.535	−6.206 to 3.136	0.497
Sex	13.653	−102.173 to 129.479	0.810	−9.551	−117.602 to 98.500	0.856	−51.103	−154.554 to 52.338	0.312
BMI	−7.858	−18.322 to 2.606	0.134				−6.199	−16.878 to 4.480	0.183
TC	2.602	−22.586 to 27.789	0.833				5.381	−22.632 to 33.394	0.690
TG	−6.561	−31.802 to 16.681	0.596				9.278	−15.815 to 34.371	0.328
FT3	−43.653	−115.857 to 28.554	0.224
FT4	−655.383	−1139.062 to −171.704	0.010				−595.752	−1094.549 to −94.956	0.022
Irisin	−1.568	−2.760 to −0.377	0.012	−1.617	−2.929 to −0.305	0.018	−1.473	−2.898 to −0.047	0.044

^♆Model 1 adjusted for age and sex; ^☧Model 2 further adjustment for sex, age, BMI, TG, TC, and FT4. .