Research Article
Irisin as a Potential Biomarker Associated with Myocardial Injuries in Patients with Severe Hypothyroidism
Table 4
Multivariate linear regression for the association of serum irisin levels with native T1 values in severe hypothyroidism patients.
| Univariate linear regression | Multivariate linear regression♆ | Multivariate linear regression☧ | value | Variables | β | 95% CI | value | β | 95% CI | value | β | 95% CI |
| Age | −0.886 | −4.880 to 3.108 | 0.651 | 0.319 | −3.494 to 4.131 | 0.864 | −1.535 | −6.206 to 3.136 | 0.497 | Sex | 13.653 | −102.173 to 129.479 | 0.810 | −9.551 | −117.602 to 98.500 | 0.856 | −51.103 | −154.554 to 52.338 | 0.312 | BMI | −7.858 | −18.322 to 2.606 | 0.134 | | | | −6.199 | −16.878 to 4.480 | 0.183 | TC | 2.602 | −22.586 to 27.789 | 0.833 | | | | 5.381 | −22.632 to 33.394 | 0.690 | TG | −6.561 | −31.802 to 16.681 | 0.596 | | | | 9.278 | −15.815 to 34.371 | 0.328 | FT3 | −43.653 | −115.857 to 28.554 | 0.224 | | | | | | | FT4 | −655.383 | −1139.062 to −171.704 | 0.010 | | | | −595.752 | −1094.549 to −94.956 | 0.022 | Irisin | −1.568 | −2.760 to −0.377 | 0.012 | −1.617 | −2.929 to −0.305 | 0.018 | −1.473 | −2.898 to −0.047 | 0.044 |
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♆Model 1 adjusted for age and sex; ☧Model 2 further adjustment for sex, age, BMI, TG, TC, and FT4. . |