Relationship between Body Roundness Index and Risk of Type 2 Diabetes in Japanese Men and Women: A Reanalysis of a Cohort Study
Table 2
Association between BRI and incident T2DM by gender in the NAGALA study.
Exposure
Nonadjusted
Adjust I
Adjust II
Adjust III
HR (95% CI)
value
HR (95% CI)
value
HR (95% CI)
value
HR (95% CI)
value
Men
BRI Z score
1.94 (1.78, 2.11)
<0.001
1.96 (1.78, 2.15)
<0.001
1.50 (1.34, 1.69)
<0.001
1.34 (1.18, 1.52)
<0.001
BRI quartile
BRI Q1
1 (reference)
1 (reference)
1 (reference)
1 (reference)
BRI Q2
1.40 (0.86, 2.30)
0.178
1.35 (0.83, 2.22)
0.228
1.04 (0.63, 1.71)
0.892
0.64 (0.38, 1.07)
0.086
BRI Q3
1.99 (1.26, 3.15)
0.003
1.80 (1.14, 2.86)
0.012
0.99 (0.61, 1.62)
0.968
0.55 (0.33, 0.92)
0.023
BRI Q4
6.09 (4.05, 9.14)
<0.001
5.35 (3.55, 8.07)
<0.001
2.13 (1.33, 3.40)
0.002
1.05 (0.64, 1.72)
0.841
P For trend
<0.001
<0.001
<0.001
0.009
Women
BRI Z score
2.12 (1.92, 2.35)
<0.001
2.11 (1.88, 2.35)
<0.001
1.68 (1.44, 1.97)
<0.001
1.48 (1.26, 1.74)
<0.001
BRI quartile
BRI Q1
1 (reference)
1 (reference)
1 (reference)
1 (reference)
BRI Q2
2.11 (0.76, 5.81)
0.15
1.96 (0.71, 5.42)
0.193
1.89 (0.68, 5.23)
0.22
1.59 (0.57, 4.43)
0.375
BRI Q3
3.59 (1.39, 9.29)
0.008
3.16 (1.22, 8.19)
0.018
2.32 (0.88, 6.11)
0.087
1.66 (0.62, 4.44)
0.313
BRI Q4
14.4 (6.17, 33.7)
<0.001
11.3 (4.77, 26.61)
<0.001
5.18 (2.05, 13.08)
<0.001
2.74 (1.05, 7.14)
0.039
P For trend
<0.001
<0.001
<0.001
0.019
Note. Adjust I model adjusts for age; Adjust II model adjusts for adjust I + alcohol intake, smoking status, fatty liver, and SBP; Adjust III model adjusts for adjust II + FPG, HbA1c, HDL-C, TG, and TC. BRI, body roundness index.
