The Central Roles of Noncoding RNA in Estrogen-Dependent Female Reproductive System Tumors

Figure 4

The interaction of lncRNAs and estrogen in endometrial cancer. Two lncRNAs, HOTAIR and NIFK-AS1, have been reported to interact with estrogen and its receptor in endometrial cancer via miRNA sponging. Solid arrow: induction; flat-ended arrow: inhibition.