G Protein-Coupled Estrogen Receptor 1 (GPER1) Mediates Aldosterone-Induced Endothelial Inflammation in a Mineralocorticoid Receptor-Independent Manner

Figure 4

Inflammatory response before and after inhibition of the PI3K pathway: (a) level of cell culture medium IL-1β; (b) ICAM-1 and VCAM-1 mRNA expression; (c) protein level IL-1β and NLRP-3. (d) Western blot of IL-1β and NLRP-3. value < 0.01 compared with G1, value < 0.001 compared with G1.

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