Research Article

The Age-Dependent Increase of Metabolic Syndrome Requires More Extensive and Aggressive Non-Pharmacological and Pharmacological Interventions: A Cross-Sectional Study in an Italian Cohort of Obese Women

Table 3

Obese patients with or without metabolic syndrome, subdivided among age ranges, having altered IDF criteria.

Evidence
IDF criteria (cut-off)18–30 (n = 98)31–40 (n = 106)41–50 (n = 196)51–60 (n = 292)61–70 (n = 239)>70 (n = 69)β1Y-Interceptp

WC (≥80 cm)
MetS+25 (100%)54 (100%)117 (100%)203 (100%)182 (100%)49 (100%)
MetS−73 (100%)52 (100%)79 (100%)89 (100%)57 (100%)20 (100%)

HDL-C (<50 mg/dl)
MetS+24 (96%)a50 (92.6%)a104 (88.9%)a146 (71, 9%)a138 (75.8%)a35 (71.4%)a−0.00611.12<0.001
MetS−39 (53.4%)20 (38.5%)18 (22.8%)6 (6.7%)4 (7.0%)0 (0.0%)−0.01210.80<0.001

Triglycerides (≥150 mg/dl)
MetS+13 (52%)a33 (61.1%)a59 (50.4%)a117 (57.6%)a93 (51.1%)a26 (53.1%)a−0.00050.570.745
MetS−2 (2.7%)1 (1.9%)4 (5.1%)2 (2.2%)1 (1.7%)0 (0.0%)−0.00030.040.559

Glucose (≥100 mg/dl)
MetS+7 (28%)a16 (29.6%)a47 (40.2%)a119 (58.6%)a114 (62.6%)a31 (63.3%)a0.0104−0.11<0.001
MetS−0 (0.0%)0 (0.0%)2 (2.5%)3 (3.4%)2 (3.5%)0 (0.0%)0.0006−0.0130.138

BP (SBP ≥130 and/or DBP≥85 mmHg)
MetS+18 (72%)a37 (68.5%)a97 (82.9%)a192 (94.6%)a176 (96.7%)a47 (95.9%)0.00690.52<0.001
MetS−6 (8.2%)14 (26.9%)34 (43.0%)58 (65.2%)36 (63.1%)18 (90.0%)0.0154−0.28<0.001

Abbreviations: DBP, diastolic blood pressure; HDL-C, high-density lipoprotein cholesterol; MetS-, negative for metabolic syndrome; MetS+, positive for metabolic syndrome; SBP, systolic blood pressure; WC, waist circumference. a: versus the corresponding MetS- subgroup (Fisher's exact test). Values of β1, Y-intercept and refer to the linear regression performed by using all data within each subgroup (MetS + or MetS-).