Research Article

Prevalence and Determinants of a Blunted Parathyroid Hormone Response in Young Saudi Women with Vitamin D Deficiency: A Cross-Sectional Study

Table 1

Distribution of age, anthropometric, and biochemical characteristics of the study group and those with or without a blunted PTH response.

VariablesAll women (n = 315), median (IQR)Blunted PTH response (n = 62), median (IQR)Elevated PTH response (n = 253), median (IQR) value

Age (years)31.0 (24.0–40.0)26.5 (22.0–37.3)32.0 (25.0–40.5)0.041
Weight (kg)67.0 (57.0–80.0)61.0 (50.9–72.3)68.0 (58.0–82.0)<0.001
Height (cm)157.0 (153.0–161.0)156.5 (153.0–160.0)157.0 (153.0–161.0)0.597
BMI (kg/m2)27.6 (22.4–32.1)25.5 (20.0–29.3)28.2 (23.1–33.2)0.001
WC (cm)79 (70–90)73.5 (65.5–80.0)80.0 (70.0–90.0)<0.001
25(OH)D (nmol/L)14.7 (10.8–21.0)18.4 (12.6–25.3)14.2 (10.0–19.9)0.002
PTH (pmol/L)10.0 (7.5–13.6)6.0 (5.2–6.4)10.9 (8.9–15.0)<0.001
Albumin (g/L)41.2 ± 3.641.6 ± 3.141.1 ± 3.70.308
C-Ca (mmol/L)2.42 (2.29–2.66)2.59 (2.35–2.75)2.37 (2.29–2.63)0.001
iPh (mmol/L)1.25 (1.13–1.38)1.30 (1.20–1.43)1.24 (1.11–1.36)0.005
Mg (mmol/L)0.800 (0.700–0.800)0.800 (0.700–0.800)0.800 (0.700–0.800)0.738
Creatinine (μmol/L)48.0 (42.8.55.0)49.5 (41.0–57.5)48.0 (43.0–54.8)0.624

According to variable distribution, Mann–Whitney test or Student’s t-test was used to compare the different variables among women with or without a blunted PTH response. : mean ± standard deviation IQR, interquartile range; BMI, body mass index; WC, waist circumference; 25(OH)D, 25 hydroxyvitamin D; PTH, parathyroid hormone; C-Ca, corrected total serum calcium; iPh, serum inorganic phosphate; and Mg, serum magnesium.