Minor Change of Plasma Renin Activity during the Saline Infusion Test Provide an Auxiliary Diagnostic Value for Primary Aldosteronism

Figure 3

Receiver-operator characteristic (ROC) curves of ΔPRA for PA diagnosis among 43 patients with an inconclusive SIT result (28 with and 15 without PA) and relabelled by AVS. The optimal cutoff value was obtained according to the highest Youden index (YI): ΔPRA ≤ 0.21 ng/ml/h (sensitivity = 71.4%; specificity = 80.0%; PPV = 87.0%; NPV = 60.0%; YI = 0.514).