Research Article
Minor Change of Plasma Renin Activity during the Saline Infusion Test Provide an Auxiliary Diagnostic Value for Primary Aldosteronism
Table 1
Comparison of characteristics and SIT parameters in PA and non-PA groups.
| | | PA (n = 159) | Non-PA (n = 368) | |
| | Age (years) | 46.8 ± 8.8 | 42.2 ± 8.2 | <0.001 | | Female | 117 (63%) | 257 (67%) | 0.255 | | BMI (kg/m2) | 27.1 ± 3.6 | 27.2 ± 3.7 | 0.890 | | Serum potassium (mmol/L) | 3.56 ± 0.39 | 3.76 ± 0.34 | 0.050 | | Hypokalemia | 42% | 20% | <0.001 | | PAC pre-SIT (ng/dl) | 21.5 (17.1, 26.5) | 16.5 (13.8, 20.9) | 0.001 | | PRA pre-SIT (ng/ml/h) | 0.35 (0.20, 0.59) | 1.92 (1.07, 2.43) | <0.001 | | ARR pre-SIT (ng/dl)/(ng/ml/h) | 61.3 (35.3, 84.8) | 9.9 (5.9, 15.5) | <0.001 | | PAC post-SIT (ng/dl) | 13.7 (10.8, 18.6) | 5.8 (8.2, 11.0) | <0.001 | | PRA post-SIT (ng/ml/h) | 0.20 (0.08, 0.28) | 0.66 (0.35, 1.20) | <0.001 | | ARR post-SIT (ng/dl)/(ng/ml/h) | 68.6 (46.3, 94.2) | 12.9 (6.7, 20.8) | <0.001 | | ΔPAC (ng/dl) | 6.9 (3.6, 10.8) | 8.50 (5.5, 11.7) | 0.127 | | ΔPRA (ng/ml/h) | 0.16 (0.05, 0.34) | 1.07 (0.52, 1.81) | <0.001 | | PAC post-SIT/ΔPRA | 57.9 (31.4, 121.6) | 8.2 (4.2, 16.0) | <0.001 |
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