Minor Change of Plasma Renin Activity during the Saline Infusion Test Provide an Auxiliary Diagnostic Value for Primary Aldosteronism

Table 3

Characteristics of 43 patients with inconclusive SIT results and completed AVS.

		Confirmed PA	Unconfirmed PA	value
		(n = 28)	(n = 15)
Age (years)		47 ± 11.2	45 ± 5.3	0.451
Female		8 (28.7%)	5 (33.3%)	0.746
BMI (kg/m^2)		27.4 ± 3.9	27.6 ± 3.38	0.844
Systolic (mmHg)		142.8 ± 16.9	134.3 ± 17.5	0.264
Diastolic (mmHg)		94.7 ± 11.0	92.5 ± 6.1	0.636
Hypokalemia (n, %)		8 (28.6%)	2 (13.3%)	0.260
PAC^∗	Pre-SIT	17.1 (13.7–20.1)	15.9 (13.3–19.1)	0.543
(ng/dl)	Post-SIT	7.4 (6.3–8.3)	7.6 (6.8–8.3)	0.118
PRA^∗	Pre-SIT	0.34 (0.25–0.46)	0.45 (0.34–0.61)	0.054
(ng/ml/h)	Post-SIT	0.17 (0.1–0.25)	0.15 (0.1–0.33)	0.785
ARR^∗	Pre-SIT	40.6 (28.1–60.2)	38.0 (25.0–44.8)	0.570
	Post-SIT	38.1 (29.7–48.9)	44.8 (22.6–58.2)	0.640
ΔPRA^∗ (ng/ml/h)		0.16 (0.04–0.28)	0.29 (0.22–0.42)	0.030

Reported values are the number of patients with available data and then number (percentages) or median (first quartile and third quartile) or mean ± standard deviation. Post-SIT PRA, plasma renin activity after the saline infusion test; ΔPRA, decrease values of plasma renin activity after the saline infusion test; Post-SIT ARR, aldosterone-to-renin ratio after the saline infusion test. ^∗Values are not normally distributed which are given as median (first quartile, third quartile).