Association between Growth Differentiation Factor-15 and Risk of Cardiovascular Diseases in Patients with Adult Growth Hormone Deficiency

Table 1

Baseline features of the AGHD patients and the healthy control group.

Variables	Control	AGHD	value
Age, y	43.53 ± 9.98	42.09 ± 12.98	0.314
BMI, kg/m^2	22.24 ± 2.57	22.94 ± 5.47	0.291
WC, cm	76.34 ± 8.55	79.45 ± 9.44	0.063
HC, cm	92.43 ± 5.83	92.07 ± 6.90	0.863
WHR	0.81 ± 0.06	0.86 ± 0.06	0.003
SBP, mmHg	114.67 ± 13.55	114.09 ± 13.77	0.554
DBP, mmHg	71.06 ± 9.22	73.44 ± 10.62	0.193
ALT, U/L	18 (13–32)	23 (15–29)	0.268
AST, U/L	19 (16–24)	23 (17–25)	0.003
Cr, umol/L	61 (53–70)	61 (58–71)	0.302
FPG, mmol/L	5.2 (4.9–5.5)	4.9 (4.6–5.3)	0.008
TC, mmol/L	4.54 (4.05–4.93)	4.50 (4.14–5.06)	0.173
TG, mmol/L	1.03 (0.84–1.52)	1.25 (0.89–1.54)	0.112
HDL-C, mmol/L	1.49 (1.28–1.79)	1.39 (1.13–1.55)	0.008
LDL-C, mmol/L	2.52 (2.14–3.12)	2.71 (2.24–3.36)	0.064
hs-CRP, mg/L	0.70 (0.26–1.16)	1.63 (0.75–1.83)	<0.001

Data were mean ± SD or median (IQR). BMI = body mass index; WC = waist circumference; HC = hip circumference; WHR = waist-hip ratio; SBP = systolic blood pressure; DBP = diastolic blood pressure; TC = total cholesterol; TG = triglycerides; HDL-C = high-density lipoprotein cholesterol; LDL-C = low-density lipoprotein cholesterol; hs-CRP = high-sensitivity C-reactive protein; AST = aspartate aminotransferase; ALT = alanine aminotransferase; Cr = creatinine; IGF-1 = insulin-like growth factor-1. and .