Association between Growth Differentiation Factor-15 and Risk of Cardiovascular Diseases in Patients with Adult Growth Hormone Deficiency

Table 2

Multivariate logistic regression analysis.

Factors	Model 1		Model 2		Model 3
	OR (95% CI)	value	OR (95% CI)	value	OR (95% CI)	value
Gender	0.576 (0.159–2.084)	0.400	0.524 (0.139–1.979)	0.341	0.528 (0.125–2.229)	0.385
Age	1.038 (0.981–1.098)	0.200	1.033 (0.976–1.094)	0.261	1.033 (0.972–1.099)	0.296
GDF-15^#	1.013 (1.002–1.025)	0.022	1.012 (1.001–1.023)	0.034	1.012 (1.001–1.024)	0.038
HOMA-IR	1.100 (0.853–1.419)	0.462	1.099 (0.854–1.416)	0.463	1.202 (0.816–1.771)	0.351
LDL-C	1.072 (0.562–2.044)	0.833	1.101 (0.557–2.179)	0.782	1.223 (0.599–2.497)	0.580
Hs-CRP	—	—	1.344 (0.876–2.061)	0.176	1.364 (0.843–2.207)	0.207
BMI	—	—	—	—	0.845 (0.672–1.062)	0.148

^#GDF-15 was an independent risk factor for cardiovascular risk after adjusting for other factors among AGHD patients who were below 60 years of age. .