Risk Factors for Severe Hypocalcemia in Patients with Secondary Hyperparathyroidism after Total Parathyroidectomy
Table 2
Preoperative indicators of patients in the SH and non-SH groups.
Severe hypocalcemia
No (n = 811)
Yes (n = 284)
Male (n, %)
475 (58.6)
172 (60.6)
0.575
Age (years)b
48.2 ± 10.8
44.6 ± 10.7
<0.001
Duration of dialysis (months)a
84 (60∼120)
84 (60∼120)
0.997
Diabetes mellitus (n, %)
39 (4.8)
6 (2.1)
0.055
Hypertension (n, %)
653 (80.3)
219 (78.4)
0.230
SBP (mmHg)b
142.0 (20.9)
142.9 (20.7)
0.528
DBP (mmHg)b
87.3 (14.7)
90.1 (15.8)
0.007
Heartbeat (beats/min)b
82.2 (11.6)
84.8 (11.9)
0.001
Clinical symptoms
Bone pain (n, %)
625 (77.1)
248 (87.3)
<0.001
Pruritus (n, %)
461 (57.0)
130 (45.8)
0.001
Preoperative laboratory test
iPTH (pg/ml)a
1239.7 (871.7∼1773.0)
2304.9 (1681.2∼2919.2)
<0.001
ALP (U/L)a
159.5 (102.8∼279.2)
528.2 (290.6∼848.3)
<0.001
Hemoglobin (g/L)b
109.3 (19.5)
103.2 (19.1)
<0.001
Albumin (g/L)b
41.9 (4.4)
41.7 (5.1)
0.563
Phosphorus (mmol/L)a
2.2 (1.9∼2.6)
2.2 (1.9∼2.5)
0.161
Calcium (mmol/L)b
2.5 (0.2)
2.4 (0.2)
<0.001
Surgical procedure
Weights of resected glands (g)a
2.4 (1.5∼3.8)
3.2 (2.0∼5.0)
<0.001
Four glands resected (n, %)
668 (85.1)
247 (89.5)
0.285
Aortic calcification (n, %)
454 (57.4)
171 (61.3)
0.507
aMedian, Q1∼Q3.b Mean ± SD. Normal ranges: iPTH (12–88 pg/ml); ALP (35–100 U/L); hemoglobin (120–160 g/L for male and 110–150 for female); albumin (40–55 g/L); phosphorus (0.85–1.51 mmol/L); and calcium (2.15–2.55 mmol/L).
