Evaluation of Thyroid Function in Patients Hospitalized for Acute Heart Failure

Table 3

Association of thyroid function (TSH and FT4) with short-term clinical endpoints.

	TSH (μIU/mL)		FT4 (ng/dL)
	OR (95% CI)	value	OR (95% CI)	value
In-hospital mortality
Unadjusted model	0.88 (0.50 to 1.55)	0.655	0.77 (0.04 to 13.95)	0.860
Model 1^a	0.95 (0.54 to 1.68)	0.854	0.71 (0.04 to 13.40)	0.818
Readmission for heart failure within 30 days
Unadjusted model	1.05 (0.77 to 1.43)	0.739	2.83 (0.84 to 9.50)	0.093
Model 1^a	1.08 (0.79 to 1.47)	0.644	2.67 (0.78 to 9.11)	0.118
All-cause mortality within 30 days
Unadjusted model	0.94 (0.64 to 1.37)	0.738	3.30 (0.88 to 12.33)	0.076
Model 1^a	0.96 (0.65 to 1.40)	0.823	3.40 (0.90 to 12.83)	0.071
Cardiovascular mortality within 30 days
Unadjusted model	0.97 (0.60 to 1.54)	0.886	6.45 (1.42 to 29.29)	0.016
Model 1^a	0.97 (0.60 to 1.57)	0.886	6.58 (1.37 to 31.48)	0.018

The values shown are odds ratios and 95% confidence intervals, estimated by uni- and multivariate logistic regressions, with TSH or FT4 as the independent variable and in-hospital mortality, hospital readmission, and all-cause and cardiovascular mortality within 30 days of discharge as dependent variables. TSH was log-transformed. TSH: thyroid-stimulating hormone; FT4: free thyroxine; OR: odds ratio; CI: confidence interval. ^aAdjusted for age and sex.