Evaluation of Thyroid Function in Patients Hospitalized for Acute Heart Failure
Table 3
Association of thyroid function (TSH and FT4) with short-term clinical endpoints.
TSH (μIU/mL)
FT4 (ng/dL)
OR (95% CI)
value
OR (95% CI)
value
In-hospital mortality
Unadjusted model
0.88 (0.50 to 1.55)
0.655
0.77 (0.04 to 13.95)
0.860
Model 1a
0.95 (0.54 to 1.68)
0.854
0.71 (0.04 to 13.40)
0.818
Readmission for heart failure within 30 days
Unadjusted model
1.05 (0.77 to 1.43)
0.739
2.83 (0.84 to 9.50)
0.093
Model 1a
1.08 (0.79 to 1.47)
0.644
2.67 (0.78 to 9.11)
0.118
All-cause mortality within 30 days
Unadjusted model
0.94 (0.64 to 1.37)
0.738
3.30 (0.88 to 12.33)
0.076
Model 1a
0.96 (0.65 to 1.40)
0.823
3.40 (0.90 to 12.83)
0.071
Cardiovascular mortality within 30 days
Unadjusted model
0.97 (0.60 to 1.54)
0.886
6.45 (1.42 to 29.29)
0.016
Model 1a
0.97 (0.60 to 1.57)
0.886
6.58 (1.37 to 31.48)
0.018
The values shown are odds ratios and 95% confidence intervals, estimated by uni- and multivariate logistic regressions, with TSH or FT4 as the independent variable and in-hospital mortality, hospital readmission, and all-cause and cardiovascular mortality within 30 days of discharge as dependent variables. TSH was log-transformed. TSH: thyroid-stimulating hormone; FT4: free thyroxine; OR: odds ratio; CI: confidence interval. aAdjusted for age and sex.