Research Article
Evaluation of Thyroid Function in Patients Hospitalized for Acute Heart Failure
Table 4
Association between inpatient parameters and long-term clinical outcomes.
| | | Unadjusted model | Age- and sex-adjusted model | | Hazard ratio (95% CI) | value | Hazard ratio (95% CI) | value |
| | All-cause mortality | | TSH (μIU/mL) | 1.02 (0.88 to 1.19) | 0.791 | 1.03 (0.88 to 1.19) | 0.733 | | FT4 (ng/dL) | 1.40 (0.69 to 2.85) | 0.350 | 1.22 (0.59 to 2.52) | 0.599 | | BNP (pg/mL) | 1.16 (0.99 to 1.36) | 0.074 | 1.16 (0.99 to 1.37) | 0.070 | | eGFR | 0.99 (0.99 to 1.00) | 0.015 | 0.99 (0.99 to 1.00) | 0.105 | | LV ejection fraction (%) | 0.98 (0.96 to 1.01) | 0.182 | 0.98 (0.96 to 1.01) | 0.146 | | PASP (mmHg) | 1.03 (1.02 to 1.05) | <0.001 | 1.03 (1.02 to 1.05) | <0.001 |
| | Cardiovascular mortality | | TSH (μIU/mL) | 1.02 (0.82 to 1.26) | 0.875 | 1.02 (0.83 to 1.27) | 0.823 | | FT4 (ng/dL) | 1.40 (0.53 to 3.71) | 0.501 | 1.33 (0.49 to 3.58) | 0.577 | | BNP (pg/mL) | 1.35 (1.08 to 1.69) | 0.007 | 1.35 (1.08 to 1.70) | 0.009 | | eGFR (mL/min/1.73 m2) | 1.00 (0.99 to 1.01) | 0.441 | 1.00 (0.99 to 1.01) | 0.518 | | LV ejection fraction (%) | 0.98 (0.95 to 1.01) | 0.268 | 0.98 (0.94 to 1.01) | 0.200 | | PASP (mmHg) | 1.04 (1.02 to 1.06) | <0.001 | 1.04 (1.02 to 1.06) | <0.001 |
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TSH and BNP were log-transformed. CI: confidence interval; TSH: thyroid-stimulating hormone; FT4: free thyroxine; BNP: B-type natriuretic peptide; eGFR: estimated glomerular filtration rate; LV: left ventricle; PASP: pulmonary arterial systolic pressure.
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