Circulating Prokineticin 2 Levels Are Increased in Children with Obesity and Correlated with Insulin Resistance

Figure 1

Circulating PK2 levels and ROC curve analysis in the study cohort. (a) Circulating PK2 levels in boys and girls (vs. boys:  < 0.01). (b) Circulating PK2 levels in children with obesity and normal-weight controls (vs. control:  < 0.001). (c) Prevalence of elevated obesity in different quartiles of PK2: quartile 1, <10654.9 pg/mL; quartile 2, 10654.9–13540.1 pg/mL; quartile 3, 13540.1–15857.4 pg/mL; quartile 4, >15857.4 pg/mL (vs. quartile 1:  < 0.05,  < 0.01,  < 0.001). (d) ROC curve analyses for the prediction of obesity according to the PK2 levels.

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