Research Article

A Nomogram Model that Predicts the Risk of Diabetic Nephropathy in Type 2 Diabetes Mellitus Patients: A Retrospective Study

Table 1

Demographic and clinical characteristics between the DN and NDN groups.

Demographic characteristicsn (%)
Total (n = 1095)DN (n = 203)NDN (n = 892)

Gender
 Female472 (43.1)77 (37.9)395 (44.3)
 Male623 (56.9)126 (62.1)497 (55.7)
Age
 <50229 (20.9)33 (16.3)196 (22.0)
 50–69699 (63.8)136 (67.0)563 (63.1)
 >69167 (15.3)34 (16.7)133 (14.9)
Smoking
 No788 (72.0)131 (64.5)657 (73.7)
 Yes307 (28.0)72 (35.5)235 (26.3)
Consuming alcohol
 No805 (73.5)136 (67.0)669 (75.0)
 Yes290 (26.5)67 (33.0)223 (25.0)
Hypertension
 No638 (58.3)82 (40.4)556 (62.3)
 Yes457 (41.7)121 (59.6)336 (37.7)
Medicine
 No233 (21.3)13 (6.4)220 (24.7)
 Yes862 (78.7)190 (93.6)672 (75.3)
Diabetes duration (years)
 <10690 (63.0)83 (40.9)607 (68.1)
 10–20371 (33.9)107 (52.7)264 (29.6)
 >2034 (3.1)13 (6.4)21 (2.3)
BMI (kg/m2)
 <24511 (46.7)82 (40.4)429 (48.1)
 24–27.99418 (38.2)85 (41.9)333 (37.3)
 ≥28166 (15.1)36 (17.7)130 (14.6)
FBG (mmol/L)
 <6.1130 (11.9)21 (10.3)109 (12.2)
 6.1–6.991 (8.3)13 (6.4)78 (8.7)
 >6.9874 (79.8)169 (83.3)705 (79.1)
PBG (mmol/L)
 <7.857 (5.2)10 (4.9)47 (5.3)
 7.8–11.0217 (19.8)44 (21.7)173 (19.4)
 >11.0821 (75.0)149 (73.4)672 (75.3)
HbA1c (%)
 <6.059 (5.4)7 (3.5)52 (5.8)
 6.0–6.9151 (13.8)21 (10.3)130 (14.6)
 >6.9885 (80.8)175 (86.2)710 (79.6)
TG (mmol/L)
 <1.7576 (52.6)106 (52.2)470 (52.7)
 ≥1.7519 (47.4)97 (47.8)422 (47.3)
TC (mmol/L)
 <6.0959 (87.6)176 (86.7)783 (87.8)
 ≥6.0136 (12.4)27 (13.3)109 (12.2)
HDL (mmol/L)
 <1.0518 (47.3)110 (54.2)408 (45.7)
 ≥1.0577 (52.7)93 (45.8)484 (54.3)
BUN (mmol/L)
 <3.294 (8.6)11 (5.4)83 (9.3)
 3.2–7.5856 (78.2)110 (54.2)746 (83.6)
 >7.5145 (13.2)82 (40.4)63 (7.1)
SCr (μmol/L)
 ≤115977 (89.2)119 (58.6)858 (96.2)
 >115118 (10.8)84 (41.4)34 (3.8)
UA (μmol/L)
 ≤420905 (82.6)142 (70.0)763 (85.5)
 >420190 (17.4)61 (30.0)129 (14.5)
Hs-CRP
 ≤8904 (82.6)155 (76.4)749 (84.0)
 >8191 (17.4)48 (23.6)143 (16.0)
WBC (×109)
 ≤10953 (87.0)163 (80.3)790 (88.6)
 >10142 (13.0)40 (19.7)102 (11.4)
N
 ≤7970 (88.6)167 (82.3)803 (90.0)
 >7125 (11.4)36 (17.7)89 (10.0)
L
 ≤3.71066 (97.4)198 (97.5)868 (97.3)
 >3.729 (2.6)5 (2.5)24 (2.7)
NLR
 <1.49281 (25.7)26 (12.8)255 (28.6)
 1.49–1.99274 (25.0)41 (20.2)233 (26.1)
 2.00–2.84267 (24.4)50 (24.6)217 (24.3)
 >2.84273 (24.9)86 (42.4)187 (21.0)
RDW (%)
 <12.0292 (26.7)35 (17.2)257 (28.8)
 12.0–12.4275 (25.1)47 (23.2)228 (25.6)
 12.5–13.0266 (24.3)55 (27.1)211 (23.6)
 >13.0262 (23.9)66 (32.5)196 (22.0)

BMI, body mass indices; FBG, fasting blood glucose; PBG, postprandial blood glucose; HbA1c, glycosylated hemoglobin A1c; TG, triglycerides; TC, total cholesterol; HDL, high‐density lipoprotein cholesterol; BUN, blood urea nitrogen; SCr, serum creatinine; UA, uric acid; Hs‐CRP, high sensitivity C‐reactive protein; WBC, white blood cell; N, neutrophil; L, lymphocyte; NLR, neutrophil to lymphocytes ratio; RDW, red blood cell distribution width.