Research Article

Positive Association between Triglyceride-Rich Lipoprotein Cholesterol and Diabetes Mellitus in Hypertensive Patients

Table 1

Characteristics of study population.

VariablesAll patients (n = 13,721)Non-DM (n = 11,284)DM (n = 2,437) value

Age (years)63.79 ± 9.4163.56 ± 9.0264.08 ± 9.870.002
Male (n) (%)6,479 (47.22)2,525 (33.13)3,954 (64.83)<0.001
BMI (kg/m2)23.57 ± 3.7523.25 ± 3.8223.98 ± 3.61<0.001
SBP (mmHg)148.53 ± 17.82149.45 ± 17.31147.39 ± 18.39<0.001
DBP (mmHg)89.04 ± 10.7688.75 ± 10.3989.40 ± 11.20<0.001
Physical activity (n) (%)
Regular exercise11,107 (80.95)9,135 (80.96)1,972 (80.92)0.967
Rarely exercise2,614 (19.05)2,149 (19.04)465 (19.08)

Fruit and vegetable consumption
≥500 g/day9,204 (82.87)7,542 (82.56)1,662 (84.28)0.066
<500 g/day1,903 (17.13)1593 (17.44)310 (15.72)

Smoking status (n) (%)
Never7,959 (58.02)6,409 (56.81)1,550 (63.63)<0.001
Former2,194 (15.99)1,815 (16.09)379 (15.56)
Current3,565 (25.99)3,058 (27.11)507 (20.81)

Drinking status (n) (%)
Never8,900 (64.88)7,201 (63.83)1,699 (69.75)<0.001
Former1,810 (13.20)1,511 (13.39)299 (12.27)
Current3,007 (21.92)2,569 (22.77)438 (17.98)

Laboratory markers
TC (mmol/L)5.18 ± 1.105.11 ± 1.055.50 ± 1.25<0.001
TG (mmol/L)1.80 ± 1.251.69 ± 1.122.28 ± 1.65<0.001
LDL-C (mmol/L)3.00 ± 0.802.95 ± 0.773.24 ± 0.87<0.001
HDL-C (mmol/L)1.57 ± 0.431.58 ± 0.421.55 ± 0.44<0.001
Non-HDL-C (mmol/L)3.61 ± 0.993.53 ± 0.953.95 ± 1.09<0.001
TRL-C (mmol/L)0.61 ± 0.470.59 ± 0.450.71 ± 0.52<0.001
FBG (mmol/L)6.17 ± 1.595.68 ± 0.568.44 ± 2.55<0.001
eGFR (ml/min/1.73 m2)88.33 ± 20.1988.67 ± 19.7286.75 ± 22.170.004
Disease and medication history (n) (%)
Self-reported stroke820 (5.98)646 (5.72)174 (7.14)0.008
Self-reported CAD633 (4.61)506 (4.48)127 (5.21)0.121
Antihypertensive drugs8,784 (64.03)7,093 (62.87)1,691 (69.42)<0.001

Values are presented as mean ± standard deviation, or n (%). DM, diabetes mellitus; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; TC, total cholesterol; TG, triglycerides; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; TRL-C, triglyceride-rich lipoprotein cholesterol; FBG, fasting blood glucose; eGFR, estimated glomerular filtration rate; CVD, cardiovascular disease.