The Influence of Treated and Untreated Subclinical Hypothyroidism on Metabolic Profile in Women with Polycystic Ovary Syndrome
Table 1
Anthropometric, thyroid, and metabolic characteristics in PCOS women with untreated SCH (non-treatment), treated SCH (treatment), and normal thyroid function (control).
Variable
Group
Value
Non-treatment n = 38
Treatment n = 76
Control n = 76
Age (years)
24.21 ± 4.19
25.24 ± 4.29
24.80 ± 3.92
0.4
BMI (kg/m2)
26.17 ± 7.01
27.12 ± 5.59
25.05 ± 6.44
0.01
TSH (mIU/L) (0.27–4.2)
5.58 ± 1.55
2.09 ± 0.92
1.62 ± 0.54
<0.0001
FT4 (pmol/L) (9.01–21.88)
13.42 ± 2.12
15.85 ± 2.58
13.69 ± 1.70
<0.001
CHOL (mmol/l) (<5.2)
4.89 ± 0.92
4.77 ± 0.9
4.72 ± 0.75
0.7
HDL-C (mmol/l) (>1)
1.35 ± 0.38
1.32 ± 0.33
1.46 ± 0.42
0.1
LDL-C (mmol/l) (<3.4)
2.94 ± 0.9
2.85 ± 0.76
2.77 ± 0.72
0.7
TRIG (mmol/l) (<1.7)
1.34 ± 0.58
1.33 ± 0.64
1.17 ± 0.5
0.3
Glucose (mmol/l) (4.08–5.84)
4.79 ± 0.35
4.88 ± 0.39
4.83 ± 0.62
0.5
Insulin [uIU/ml] (<24)
11.08 ± 7.26
10.40 ± 6.00
9.44 ± 6.12
0.2
HOMA-IR
2.41 ± 1.67
2.31 ± 1.44
2.10 ± 1.57
0.2
BMI, body mass index; FT4 – free thyroxine; CHOL, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, light-density lipoprotein cholesterol; TRIG, triglycerides; HOMA-IR, homeostatic assessment of insulin resistance.
