Immunohistochemistry for (Pro)renin Receptor in Humans

Table 2

Distribution of (pro)renin receptor expression in organs outside the brain.

	Case 1	Case 2	Case 3
Thyroid
Follicular epithelial cell	+	−	+
Lymph duct	−	−	−
Lung
Alveoli epithelial cell	−	−	−
Blood vessel	−	−	−
Liver
Hepatic cell	+	+	+
Epithelial cell	−	−	−
Cholangioepithelial cell	−	−	−
Blood vessel	−	−	−
Lymph duct	−	−	−
Pancreas
Acinar cell	−	−	−
Pancreatic duct epithelial cell	−	−	+
Islets of Langerhans	−	−	−
Blood vessel	−	−	−
Lymph duct	−	−	−
Adrenal gland
Zona glomerulosa	+	−	+
Zona fasciculate	−	−	−
Zona reticularis	−	−	±
Medulla	+	−	+
Kidney
Glomerulus	−	−	−
Proximal tubule	−	+	+
Distal tubule	±	+	+
Collecting duct	+	+	+
Blood vessel	−	−	−
Lymph duct	−	−	−
Skeletal muscle
Lingual muscle	N/A	−	+
Diaphragm	+	N/A	+
Iliopsoas muscle	N/A	N/A	±
Cardiomyocytes	+	+	+
Smooth muscle
Aorta	N/A	−	+
Colon	±	−	−

The immunostaining intensity in the cytoplasm was evaluated on a scale of − (no staining), ± (borderline staining), and + (positive staining). N/A, not available.