International Journal of Endocrinology

Research Article

Immunohistochemistry for (Pro)renin Receptor in Humans

Table 3

Distribution of (pro)renin receptor expression in the brain.
 Case 1Case 2Case 3
Brain stem
 Medulla
  Nucleus tractus solitarii+++
  Dorsal nucleus of vagus+++
  Hypoglossal nucleus+++
  Inferior olivary nucleus+++
 Midbrain   
  Thalamus+++
  Lateral nucleus+++
  Medial nucleus+++
 Hypothalamus
  Paraventricular nucleus+++
  Supraoptic nucleusN/A++
  Mammillary body+++
Cerebrum
  Grey matter+++
  White matter+N/AN/A
  Hippocampus
   Stratum radiatum±++
   Pyramidal cell layer+++
   Stratum lacunosum±++
Cerebellum
  Molecular layer±±±
  Purkinje cell layer+++
  Granular layer±±±
Pituitary
  Anterior lobe+++
  Posterior lobe−−+
The immunostaining intensity in the cytoplasm was evaluated on a scale of − (no staining), ± (borderline staining), and + (positive staining). N/A, not available.