Relationship of Serum Total Insulin-Like Growth Factor Binding Protein-3 with Insulin-Like Growth Factor-I and Glucose Tolerance in Korean Children and Adolescents
Table 1
Demographic features of the study participants.
Characteristic
Total
NGT
Glucose intolerance
value (NGT versus IGT versus DM)
IGT
DM
Subtotal
Number (%)
187 (100.0)
115 (61.5)
33 (17.6)
39 (20.9)
72
Age (years)
12.51 ± 3.45
11.76 ± 3.56
12.83 ± 3.04
14.47 ± 2.54†
13.72 ± 2.88
<0.001
Sex (%)
Female
98 (52.4)
51 (44.3)
20 (60.6)
27 (69.2)
47 (65.3)
0.004
Male
89 (47.6)
64 (55.7)
13 (39.4)
12 (30.8)
25 (34.7)
Family history of DM in the first-degree relatives
63 (33.7)
24 (20.9)
16 (48.5)
23 (59.0)
39 (54.2)
<0.001
BMI (kg/m2)
24.50 ± 5.12
23.95 ± 4.68
25.20 ± 6.19
25.54 ± 5.29
25.39 ± 5.68
0.170
Normal
59 (31.6)
36 (31.3)
8 (24.2)
15 (38.5)
23 (31.9)
0.998
Overweight
42 (22.5)
30 (26.1)
5 (15.2)
7 (17.9)
12 (16.7)
Obesity
86 (46.0)
49 (42.6)
20 (60.6)
17 (43.6)
37 (51.4)
The data are presented as mean ± SD values. NGT, normal glucose tolerance; IGT, impaired glucose tolerance; DM, type 2 diabetes mellitus; BMI, body mass index; SD, standard deviation.