Relationship of Serum Total Insulin-Like Growth Factor Binding Protein-3 with Insulin-Like Growth Factor-I and Glucose Tolerance in Korean Children and Adolescents

Table 4

Simple correlation (γ) analysis between serum IGF-I and clinical variables.

		NGT (n = 115)		IGT (n = 33)		DM (n = 39)
			γ		γ		γ
IGF-I	Age	<0.001	0.475	0.612	0.093	0.353	−0.159
	BMI	0.895	−0.013	0.487	0.127	0.080	−0.296
	FPG	0.014	0.242	0.482	−0.129	0.001	0.544
	2 hr PLG	0.965	0.004	0.252	−0.208	0.729	0.060
	Cholesterol	0.459	−0.074	0.514	0.120	0.820	−0.039
	Triglyceride	0.914	0.011	0.214	0.226	0.354	−0.159
	HDL	0.454	0.075	0.876	0.029	0.338	0.164
	LDL	0.148	−0.144	0.862	−0.032	0.897	−0.022
	HOMA-IR	0.004	0.294	0.349	0.184	0.176	0.268
	HbA1c	0.039	0.204	0.717	−0.067	0.028	0.367
	C-peptide	0.001	0.330	0.142	0.270	0.609	−0.088
	Insulin	0.008	0.270	0.279	0.212	0.914	−0.022
	IGFBP-3	<0.001	0.547	0.085	0.315	0.029	0.368

NGT, normal glucose tolerance; IGT, impaired glucose tolerance; DM, type 2 diabetes. BMI, body mass index; HbA1c, glycosylated hemoglobin; FPG, fasting plasma glucose; 2 hr PLG, 2-hour postload glucose; HOMA-IR, homeostasis model assessment of insulin resistance; LDL, low-density lipoprotein; HDL, high-density lipoprotein; IGF-I, insulin-like growth factor-I; IGFBP-3, insulin-like growth factor binding protein-3.