Relationship of Serum Total Insulin-Like Growth Factor Binding Protein-3 with Insulin-Like Growth Factor-I and Glucose Tolerance in Korean Children and Adolescents

Table 5

Simple correlation (γ) between serum IGFBP-3 and clinical variables.

		NGT (n = 115)		IGT (n = 33)		DM (n = 39)
			γ		γ		γ
IGFBP-3	Age	0.002	0.307	0.973	0.006	0.625	0.086
	BMI	0.031	0.215	0.006	0.480	0.967	−0.007
	FPG	0.117	0.158	0.304	0.191	0.012	0.421
	2 hr PLG	0.682	0.041	0.225	0.224	0.086	−0.294
	Cholesterol	0.547	0.061	0.029	0.392	0.008	0.442
	Triglyceride	0.008	0.266	0.013	0.441	0.200	0.222
	HDL	0.997	0.000	0.145	−0.268	0.529	0.110
	LDL	0.785	−0.028	0.018	0.423	0.047	0.354
	HOMA-IR	0.019	0.242	<0.001	0.670	0.294	−0.210
	HbA1c	0.003	0.296	0.019	0.420	0.004	0.477
	C-peptide	0.010	0.259	<0.001	0.661	0.068	−0.312
	Insulin	0.021	0.237	<0.001	0.626	0.070	−0.354
	IGF-I	<0.001	0.547	0.085	0.315	0.029	0.368

NGT, normal glucose tolerance; IGT, impaired glucose tolerance; DM, type 2 diabetes. BMI, body mass index; HbA1c, glycosylated hemoglobin; FPG, fasting plasma glucose; HOMA-IR, homeostasis model assessment of insulin resistance; LDL, low-density lipoprotein; HDL, high-density lipoprotein; IGF-I, insulin-like growth factor-I; IGFBP-3, insulin-like growth factor binding protein-3.