Research Article
TET3 Mediates 5hmC Level and Promotes Tumorigenesis by Activating AMPK Pathway in Papillary Thyroid Cancer
Table 3
Relationship between 5hmc positive and clinicopathological factors in patients with papillary thyroid carcinoma (n = 50).
| Characteristics | Amount | 5hmc staining | value | Positive | Negative |
| Gender | Male | 11 | 6 | 5 | 0.38 | Female | 39 | 26 | 13 | |
| Age | ≥45 years | 15 | 9 | 6 | 0.65 | <45 years | 35 | 23 | 12 | |
| Microcancer | Yes | 9 | 1 | 8 | 0.03 | No | 41 | 31 | 10 | |
| Lateral | Unilateral | 36 | 24 | 12 | 0.58 | Bilateral | 14 | 8 | 6 | |
| Focus number | Unifocal | 27 | 10 | 17 | 0.04 | Multifocal | 23 | 22 | 1 | |
| Extraglandular invasion | Yes | 49 | 32 | 17 | 0.00 | No | 1 | 0 | 1 | |
| Lymph node metastasis | Yes | 41 | 31 | 10 | 0.01 | No | 9 | 1 | 8 | |
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