The Effect of Time-Restricted Eating on Insulin Levels and Insulin Sensitivity in Patients with Polycystic Ovarian Syndrome: A Systematic Review

Figure 1

Hyperinsulinemia downstream effects on ovarian theca cell hyperproduction of androgens and subsequent pituitary feedback causing increased basal luteinizing hormone. Hyperandrogenism results in reduced SHBG (sex hormone binding globulin) (often used clinically for assessment of insulin resistance in PCOS).