Review Article

The Effect of Time-Restricted Eating on Insulin Levels and Insulin Sensitivity in Patients with Polycystic Ovarian Syndrome: A Systematic Review

Figure 4

Cellular metabolic pathways and responses to intermittent fasting showing downstream cascade effects of fasting and resulting beneficial outcomes {NAD+ (nicotinamide adenine dinucleotide); transcription factors FOXOs (forkhead box Os), PGC-1α (proliferator-activated receptor γ coactivator 1α), and NRF2 (nuclear factor erythroid 2-related factor 2); kinases AMPK (AMP kinase) and cAMP cyclic AMP; and deacetylases sirtuins (SIRTs); mammalian target of rapamycin (mTOR); insulin-like growth factor 1 (IGF-1)}.