Research Article

Impact of Visit-to-Visit Triglyceride-Glucose Index Variability on the Risk of Cardiovascular Disease in the Elderly

Table 1

Baseline characteristics according to the quartiles of TyG variability.

TotalQ1 (0–0.17)Q2 (0.17–0.27)Q3 (0.27–0.42)Q4 (0.42–3.03)

Demographic characteristics
N27,5206,8806,8806,8806,880
 Age, years66.8 (5.2)67.2 (5.3)66.9 (5.2)66.7 (5.2)66.2 (4.9)<0.001
 Female14,232 (52%)3,450 (50%)3,520 (51%)3,576 (52%)3,686 (54%)0.14
 Waist, cm83.5 (8.8)83.3 (9.0)83.4 (8.7)83.5 (8.9)83.8 (8.6)0.006
 BMI, kg/m224.4 (3.4)24.3 (3.4)24.3 (3.3)24.4 (3.5)24.6 (3.4)<0.001
 Smoking statue0.14
 Ever smoking6,209 (23%)1,586 (23%)1,599 (23%)1,518 (22%)1,506 (22%)
 Never21,311 (77%)5,294 (77%)5,281 (77%)5,362 (78%)5,374 (78%)
 Exercise status0.04
 Not active15,706 (57%)3,842 (56%)3,928 (57%)3,961 (58%)3,975 (58%)
 Somewhat active2,724 (10%)672 (10%)665 (10%)667 (10%)720 (10%)
 Regularly active9,090 (33%)2,366 (34%)2,287 (33%)2,252 (33%)2,185 (32%)
Clinical characteristics
 Diabetes3,399 (12%)616 (9%)687 (10%)871 (13%)1,225 (18%)<0.001
 Hypertension12,893 (47%)3,044 (44%)3,160 (46%)3,226 (47%)3,463 (50%)<0.001
 SBP, mmHg139.6 (19.0)139.1 (19.1)139.3 (18.9)139.7 (18.8)140.3 (19.0)0.002
 DBP, mmHg80.6 (10.5)80.3 (10.7)80.4 (10.6)80.6 (10.3)80.9 (10.3)0.005
 LDL-C, mmol/L2.8 (0.9)2.8 (0.9)2.8 (0.9)2.9 (0.9)2.8 (0.9)0.024
 HDL-C, mmol/L1.47 (0.5)1.51 (0.6)1.48 (0.5)1.48 (0.5)1.43 (0.5)<0.001
 Mean TyG (mg/dL)28.74 (0.5)8.64 (0.5)8.68 (0.5)8.74 (0.5)8.92 (0.6)<0.001

Data are presented as mean (SD) for continuous variables or n (%) for categorical variables. Q, quartile; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; TyG, triglyceride-glucose.