Research Article

Serum 25(OH)D Levels Modify the Association between Triglyceride and IR: A Cross-Sectional Study

Table 1

Baseline characteristics of the study participants.

VariablesTotal (n = 19,926)IR negative (n = 11,251)IR positive (n = 8,675) value

Age, mean ± SD47.4 ± 19.246.1 ± 19.549.1 ± 18.7<0.001
Gender, n (%)
 Male9,563 (48.0)5,285 (47)4,278 (49.3)0.001
 Female10,363 (52.0)5,966 (53)4,397 (50.7)
Race, n (%)
 Mexican American3,578 (18.0)1,745 (15.5)1,833 (21.1)<0.001
 Other Hispanic4,007 (20.1)2,162 (19.2)1,845 (21.3)
 Non-Hispanic white8,981 (45.1)5,449 (48.4)3,532 (40.7)
 Non-Hispanic black1,656 (8.3)831 (7.4)825 (9.5)
 Other races1,704 (8.6)1,064 (9.5)640 (7.4)
Education, n (%)
 Poorly educated2,330 (11.7)1,151 (10.2)1,179 (13.6)<0.001
 Moderately educated7,544 (37.9)4,099 (36.4)3,445 (39.7)
 Highly educated10,052 (50.4)6,001 (53.3)4,051 (46.7)
BMI, mean ± SD28.6 ± 6.725.8 ± 4.932.2 ± 7.1<0.001
Waist, mean ± SD97.9 ± 16.290.9 ± 12.8107.0 ± 15.6<0.001
Hypertension, n (%)
 No12,444 (62.5)7,902 (70.2)4,542 (52.4)<0.001
 Yes7,482 (37.5)3,349 (29.8)4,133 (47.6)
DM, n (%)
 No16,537 (83.0)10,394 (92.4)6,143 (70.8)<0.001
 Yes3,389 (17.0)857 (7.6)2,532 (29.2)
Alcohol, n (%)
 No15,810 (79.3)8,547 (76)7,263 (83.7)<0.001
 Yes4,116 (20.7)2,704 (24)1,412 (16.3)
Smoke, n (%)
 Never smoking10,890 (54.7)7,898 (70.2)2,646 (30.5)<0.001
 Former smokers4,942 (24.8)2,813 (25)2,134 (24.6)
 Current smokers4,094 (20.5)540 (4.7)3,895 (44.9)
HDL, median(IQR), mmol/L1.3 (1.1, 1.6)1.4 (1.2, 1.8)1.2 (1.0, 1.4)<0.001
TG, median (IQR), mmol/L1.2 (0.8, 1.8)1.0 (0.7, 1.4)1.5 (1.0, 2.2)<0.001
ALT, median (IQR), U/L20.0 (16.0, 28.0)19.0 (15.0, 25.0)23.0 (17.0, 32.0)<0.001
AST, median (IQR), U/L23.0 (19.0, 27.0)22.0 (19.0, 26.0)23.0 (19.0, 28.0)<0.001
TBIL, median(IQR), μmol/L12.0 (8.6, 15.4)12.0 (10.3, 15.4)12.0 (8.6, 13.7)<0.001
BUN, median(IQR), mmol/L4.3 (3.6, 5.4)4.3 (3.2, 5.4)4.3 (3.6, 5.7)<0.001
ALB, median (IQR), g/L42.0 (40.0, 45.0)43.0 (41.0, 45.0)42.0 (40.0, 44.0)<0.001
25(OH)D, median (IQR), ng/ml59.1 (43.3, 76.2)62.2 (45.9, 80.1)54.8 (40.0, 70.8)<0.001

DM, diabetes mellitus; HDL, high-density lipoprotein; TG, triglyceride; ALT, alanine transaminase; AST, aspartate transaminase; TBIL, total bilirubin; BUN, blood urea nitrogen; ALB, albumin; and vitd, 25(OH)D.