Research Article

The Determinants of Adolescent Glycolipid Metabolism Disorder: A Cohort Study

Table 3

The prevalence of glycolipid metabolism for adolescent according to perinatal and childhood experiences.

VariablesHOMA-IR (>3)DyslipidemiaPrediabetes
PrevalencePrevalencePrevalence

Sample size416 (21.02%)436 (21.61%)67 (7.19%)
Region
 Urban336 (22.86%)<0·01309 (20.7%)0.0928 (6.91%)0.78
 Rural80 (15.72%)127 (24.19%)39 (7.40%)
Anthropometric measures
 Sex
  Male205 (19.86%)0.19223 (21.2%)0.6441 (8.17%)0.21
  Female211 (22.28%)213 (22.05%)26 (6.05%)
 Age, y
  ∼1044 (15.17%)<0·0149 (16.55%)0.037 (6.67%)0.74
  ∼11205 (19.51%)252 (23.53%)39 (7.80%)
  ≥12167 (26.18%)135 (20.74%)21 (6.42%)
 Pubertal development
  No276 (23.08%)<0·01262 (21.56%)0·9634 (7.80%)0.69
  Yes96 (17.55%)120 (21.47%)29 (7.09%)
 Dyslipidemia, in 2014
  No138 (18.42%)0·06114 (15.64%)<0·0128 (8.75%)0.12
  Yes61 (23.74%)96 (32.65%)5 (4.31%)
 Obesity, in 2014
  Normal200 (17.33%)<0·01242 (20.46%)<0·0134 (6.19%)0.06
  Overweight56 (29.63%)44 (22.92%)6 (6.19%)
  Obesity73 (38.42%)60 (31.41%)16 (11.85%)
 Obesity, in 2019
  Normal245 (16.21%)<0·01281 (18.33%)<0·0141 (6.35%)0.15
  Overweight89 (32.36%)86 (30.71%)6 (5.94%)
  Obesity81 (44.75%)64 (34·78%)18 (10.47%)
 Abdominal obesity, in 2014
  Normal243 (19.57%)<0·01265 (20.88%)0.0539 (6.20%)0.02
  Abdominal obesity64 (32.99%)53 (26.9%)15 (11.90%)
 Abdominal obesity, in 2019
  Normal287 (17.28%)<0·01321 (19.04%)<0·0145 (6.27%)0.07
  Abdominal obesity127 (41.91%)108 (35.06%)20 (9.95%)

Perinatal measures
 Maternal prepregnancy obesity
  Low weight241 (22.25%)0.12221 (20.16%)0.0636 (7.33%)0.02
  Normal weight57 (17.87%)84 (26.09%)3 (2.17%)
  Overweight/obesity37 (25.52%)35 (23.33%)9 (11.69%)
 Maternal pregnancy weight gain
  Below IOM guidelines105 (22.01%)0.9896 (19.92%)0.4516 (7.21%)0.55
  Within IOM guidelines129 (21.57%)140 (23.1%)22 (7.64%)
  Above IOM guidelines100 (21.65%)102 (21.75%)10 (5.15%)
 Premature delivery
  No317 (21.40%)0.53316 (21%)0.1247 (6.98%)0.79
  Yes44 (23.40%)49 (25.93%)5 (6.17%)
 Fatal weight of pregnancy week
  SGA226 (20.68%)0.03236 (21.22%)0.7235 (7.09%)0.91
  Appropriate for GA20 (15.75%)24 (18.75%)4 (5.88%)
  LGA99 (25.52%)87 (22.14%)13 (7.43%)
 Gestational hypertension
  No384 (21.03%)0.83399 (21.45%)0.4861 (7.30%)0.85
  Yes12 (22.22%)14 (25.45%)2 (8.33%)
 Gestational diabetes
  No393 (21.14%)0.62409 (21.59%)0.6363 (7.35%)0.37
  Yes7 (25.00%)5 (17.86%)0 (0.00%)
 Birth with Cesarean operation
  No132 (20.06%)0.34139 (20.81%)0.5122 (6.92%)0.87
  Yes245 (21.99%)250 (22.12%)35 (7.22%)
 Breast-feeding
  No43 (23.24%)0.5546 (24.6%)0.405 (5.32%)0.47
  Yes207 (21.27%)217 (21.83%)42 (7.38%)

Socioeconomic measures
 Income, Yuan/year
  ∼50,000114 (18.84%)0.02146 (23.78%)0.2127 (8.39%)0.51
  ∼150,000161 (20.43%)160 (19.88%)24 (6.47%)
  >150,000122 (25.42%)105 (21.47%)12 (6.09%)
 Marriage status
  Double parents349 (21.33%)0.47356 (21.42%)0.4456 (7.49%)0.30
  Single parents28 (18.79%)36 (24.16%)3 (4.17%)
 Mother’s education, y
  ∼9125 (19.20%)0.05153 (22.97%)0.4124 (6.02%)0.43
  ∼12132 (19.76%)145 (21.45%)25 (8.59%)
  ≥15149 (24.31%)125 (19.94%)17 (7.56%)
 Father’s education, y
  ∼9102 (18.44%)<0.01128 (22.78%)0.4423 (6.69%)0.74
  ∼12134 (19.20%)157 (22.11%)26 (8.12%)
  ≥15170 (25.00%)139 (19.97%)17 (6.77%)
 Mother’s occupation
  Manager29 (27.36%)0.6132 (29.91%)0.096 (11.32%)0.81
  Worker135 (20.58%)133 (19.79%)21 (6.58%)
  Technician/researcher13 (21.31%)10 (16.39%)2 (8.00%)
  Farmer110 (20.87%)126 (23.55%)20 (7.49%)
  Other119 (20.70%)121 (20.65%)17 (6.88%)
 Father’s occupation
  Manager35 (22.15%)0.0933 (20.50%)0.557 (10.29%)0.53
  Worker130 (19.55%)136 (20.09%)28 (8.31%)
  Technician/researcher47 (29.19%)32 (19.39%)5 (8.62%)
  Farmer106 (19.78%)129 (23.71%)17 (6.46%)
  Other84 (21.37%)89 (22.19%)9 (5.03%)

a, b ,cDifference of post hoc analyses among groups; different letters mean the difference existed between two groups. dNatural logarithmic transformation was used to calculate the value. e932 samples were included. f; g. SGA: small for gestational age, GA: gestational age, LGA: large for gestational age.