Research Article
Association of ANKRD55 Gene Polymorphism with HT: A Protective Factor for Disease Susceptibility
Table 2
Clinical features of subjects including AITD patients and controls.
| Items | AITD | GD | HT | Controls |
| Number | 1220 | 753 | 467 | 830 |
| Gender | Male | 283 (23.20%) | 212 (28.15%) | 71 (15.20%) | 329 (39.64%) | Female | 937 (76.80%) | 541 (71.85%) | 396 (84.80%) | 501 (60.36%) | Age (years) | 41.71 ± 14.20 | 41.35 ± 14.45 | 42.29 ± 13.78 | 38.77 ± 10.39 |
| Family history | (+) | 225 (18.44%) | 147 (19.52%) | 78 (16.70%) | — | (−) | 995 (81.56%) | 606 (80.48%) | 389 (83.30%) | — |
| Ophthalmopathy | (+) | — | 108 (14.34%) | — | — | (−) | — | 645 (85.66%) | — | — |
| Hypothyroidism | (+) | — | — | 197 (42.18%) | — | (−) | — | — | 270 (57.82%) | — |
| Goiter | No goiter | 456 (37.38%) | 223 (29.61%) | 233 (49.89%) | — | Degree I | 299 (24.51%) | 193 (25.63%) | 106 (22.70%) | — | Degree II | 416 (34.10%) | 296 (39.31%) | 120 (25.70%) | — | Degree III | 49 (4.02%) | 41 (5.44%) | 8 (1.71%) | — |
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AITD, autoimmune thyroid diseases; GD, graves’ disease; HT, hashimoto’s thyroiditis.
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