Research Article

Association of ANKRD55 Gene Polymorphism with HT: A Protective Factor for Disease Susceptibility

Table 2

Clinical features of subjects including AITD patients and controls.

ItemsAITDGDHTControls

Number1220753467830

Gender
 Male283 (23.20%)212 (28.15%)71 (15.20%)329 (39.64%)
 Female937 (76.80%)541 (71.85%)396 (84.80%)501 (60.36%)
 Age (years)41.71 ± 14.2041.35 ± 14.4542.29 ± 13.7838.77 ± 10.39

Family history
 (+)225 (18.44%)147 (19.52%)78 (16.70%)
 (−)995 (81.56%)606 (80.48%)389 (83.30%)

Ophthalmopathy
 (+)108 (14.34%)
 (−)645 (85.66%)

Hypothyroidism
 (+)197 (42.18%)
 (−)270 (57.82%)

Goiter
 No goiter456 (37.38%)223 (29.61%)233 (49.89%)
 Degree I299 (24.51%)193 (25.63%)106 (22.70%)
 Degree II416 (34.10%)296 (39.31%)120 (25.70%)
 Degree III49 (4.02%)41 (5.44%)8 (1.71%)

AITD, autoimmune thyroid diseases; GD, graves’ disease; HT, hashimoto’s thyroiditis.