A Comparison of the Blood Glucose, Growth Hormone, and Cortisol Responses to Two Doses of Insulin (0.15 U/kg vs. 0.10 U/kg) in the Insulin Tolerance Test: A Single-Centre Audit of 174 Cases
Table 1
Patient characteristics and baseline biochemistry results.
Standard dose (0.15 U/kg) (n = 113)
Low dose (0.1 U/kg) (n = 61)
Total (n = 174)
Sex n (%)
Male
49 (43.4%)
21 (34.4%)
70 (40.2%)
Female
64 (56.6%)
40 (65.6%)
104 (59.8%)
Age (years)
44.7 ± 11.9 (42.5–46.9)
41.4 ± 12.4 (38.36–44.6)
43.5 ± 12.1 (41.7–45.4)
BMI† (kg/m2)
28.8 ± 18.7 (24.7–32.9)
25.2 ± 4.8 (23.8–26.5)
27.4 ± 15.1 (24.8–30.0)
Glucose (mmol/L)
4.6 ± 0.5 (4.5–4.7)
4.5 ± 0.7 (4.4–4.7)
4.6 ± 0.6 (4.5–4.7)
Growth hormone (µg/L)
0.8 ± 1.5 (0.5–1.1)
1.1 ± 2.9 (0.4–1.9)
0.9 ± 2.1 (0.6–1.2)
IGF-1†† (nmol/L)
183.3 ± 101.4 (159.1–207.5)
146.7 ± 71.4 (120.9–172.4)
171.8 ± 94.3 (153.3–190.3)
Cortisol (nmol/L)
246.7 ± 107.0 (226.0–267.3)
206.3 ± 96.7 (181.4–231.3)
232.1 ± 104.9 (216.0–248.2)
Values are depicted as mean ± standard deviation (95% confidence intervals); †: standard: n = 81, low dose: n = 50; ††: standard: n = 70, low dose: n = 32; vs. low dose.
