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International Journal of Endocrinology
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International Journal of Endocrinology
/
2023
/
Article
/
Tab 1
/
Research Article
CS27109, A Selective Thyroid Hormone Receptor-
β
Agonist Alleviates Metabolic-Associated Fatty Liver Disease in Murine Models
Table 1
AC
50
of THR-
α
and THR-
β
and selectivity of THR-
α
/THR-
β
for CS27109 and MGL3196.
Compound
CS27109
MGL3196
T3
AC
50
(
μ
M)
β
1.980
21.32
0.002780
α
25.09
192.1
0.002481
Selectivity (
α
/
β
)
12.67
9.01
0.89