Effects of 18 Months of Growth Hormone Replacement Therapy on Bone Mineral Density in Patients with Adult Growth Hormone Deficiency: A Retrospective Study
Table 3
Physical data, body composition, and QoL changes after 18 months of rhGH replacement in 36 patients.
Baseline
18 months
Sex (males/females)
7/29
7/29
1
Height (cm)
158.51 ± 8.58
158.55 ± 8.52
0.639
Weight (kg)
58.94 ± 10.47
58.75 ± 9.48
0.694
BMI (kg/m2)
23.34 ± 2.67
23.28 ± 2.59
0.754
WC (cm)
81.22 ± 9.47
80.73 ± 9.31
0.404
HC (cm)
93.68 ± 6.59
93.43 ± 6.34
0.635
WHR
0.87 ± 0.65
0.86 ± 0.64
0.502
Grip strength (kg)
26.61 (20.85, 28.25)
28.67 (23.05, 29.6)
0.003
SBP (mm Hg)
108.9 ± 10.4
108.5 ± 9.1
0.790
DBP (mm Hg)
73.6 ± 8.0
71.0 ± 5.1
0.036
BFM (g)
19994.3 ± 4652.7
19382.6 ± 4289.4
0.094
LBM (g)
37570.7 (31668.9, 41437.3)
38006.0 (32892.7, 42802.7)
0.012
Body lean/fat ratio
1.97 (1.60, 2.18)
2.06 (1.59, 2.39)
0.003
TBF (%)
33.64 (30.6, 37.7)
32.78 (28.5, 37.3)
0.011
VAT (g)
421.89 ± 160.55
393.14 ± 151.70
0.016
QoL (scores)
6.06 (2.00, 10.00)
3.14 (1.00, 3.75)
<0.001
Data are expressed as the mean ± SD or M ( and ).;;.