Research Article

Effects of 18 Months of Growth Hormone Replacement Therapy on Bone Mineral Density in Patients with Adult Growth Hormone Deficiency: A Retrospective Study

Table 3

Physical data, body composition, and QoL changes after 18 months of rhGH replacement in 36 patients.

Baseline18 months

Sex (males/females)7/297/291
Height (cm)158.51 ± 8.58158.55 ± 8.520.639
Weight (kg)58.94 ± 10.4758.75 ± 9.480.694
BMI (kg/m2)23.34 ± 2.6723.28 ± 2.590.754
WC (cm)81.22 ± 9.4780.73 ± 9.310.404
HC (cm)93.68 ± 6.5993.43 ± 6.340.635
WHR0.87 ± 0.650.86 ± 0.640.502
Grip strength (kg)26.61 (20.85, 28.25)28.67 (23.05, 29.6)0.003
SBP (mm Hg)108.9 ± 10.4108.5 ± 9.10.790
DBP (mm Hg)73.6 ± 8.071.0 ± 5.10.036
BFM (g)19994.3 ± 4652.719382.6 ± 4289.40.094
LBM (g)37570.7 (31668.9, 41437.3)38006.0 (32892.7, 42802.7)0.012
Body lean/fat ratio1.97 (1.60, 2.18)2.06 (1.59, 2.39)0.003
TBF (%)33.64 (30.6, 37.7)32.78 (28.5, 37.3)0.011
VAT (g)421.89 ± 160.55393.14 ± 151.700.016
QoL (scores)6.06 (2.00, 10.00)3.14 (1.00, 3.75)<0.001

Data are expressed as the mean ± SD or M ( and ). ; ; .