Adiponectin Gene Polymorphisms and Possible Susceptibility to Metabolic Syndrome among the Sudanese Population: A Case-Control Study

Table 4

Comparison between ADIPOQ (rs266729, rs2241766, and rs1501299) gene polymorphisms and metabolic syndrome components in MetS patients.

Genotypes	BMI (kg/m^2)	WC (cm)	SBP (mmHg)	DBP (mmHg)	HbA1c (%)	TG (mg/dL)	TC (mg/dL)	LDL-C (mg/dL)	HDL-C (mg/dL)
ADIPOQ rs266729
CC	30.79 ± 4.7	109.3 ± 11.1	134.0 ± 15.4	85.0 ± 7.6	8.66 ± 2.0	161.1 ± 53.6	182.6 ± 34.4	109.1 ± 34.6	45.1 ± 14.1
CG	32.03 ± 6.1	109.2 ± 10.4	137.7 ± 14.7	85.5 ± 6.4	9.16 ± 2.4	161.3 ± 46.5	186.6 ± 29.6	117.7 ± 26.7	45.4 ± 13.0
GG	31.60 ± 5.4	113.5 ± 7.8	135.8 ± 11.1	86.1 ± 5.0	9.22 ± 2.5	185.0 ± 69.8	184.1 ± 22.6	112.7 ± 25.2	40.4 ± 15.4
value	0.335	0.393	0.329	0.833	0.303	0.297	0.758	0.278	0.492
ADIPOQ rs2241766
TT	30.99 ± 5.3	109.6 ± 10.8	134.2 ± 14.7	85.0 ± 6.2	8.70 ± 2.2	156.2 ± 51.1^a	182.9 ± 33.2^a	109.7 ± 31.2^a	46.0 ± 14.5
TG	31.22 ± 4.7	109.1 ± 10.8	136.9 ± 16.3	85.8 ± 9.4	9.07 ± 1.9	170.1 ± 54.6^b	181.5 ± 32.5^b	109.9 ± 33.4^b	42.8 ± 12.8
GG	32.31 ± 5.9	110.2 ± 11.5	133.5 ± 11.5	84.5 ± 4.9	8.80 ± 2.2	210.8 ± 50.4	206.1 ± 17.9	141.4 ± 34.0	40.6 ± 9.3
value	0.729	0.936	0.512	0.778	0.558		0.081		0.210
ADIPOQ rs1501299
GG	30.78 ± 5.5	110.1 ± 10.3	134.4 ± 14.6	85.7 ± 7.1	8.54 ± 1.9	158.1 ± 45.6^d	178.6 ± 29.5^d	109.5 ± 32.0^d	43.6 ± 13.4
GT	31.34 ± 4.6	109.4 ± 10.7	133.5 ± 13.4^c	84.8 ± 7.2	8.94 ± 2.3	159.6 ± 50.2^c	183.2 ± 31.9^c	108.6 ± 32.1^c	45.8 ± 13.8
TT	31.21 ± 5.8	108.7 ± 12.4	140.4 ± 19.5	85.4 ± 7.4	9.00 ± 2.2	182.5 ± 72.6	196.2 ± 39.4	123.4 ± 33.1	44.8 ± 15.6
value	0.771	0.789	0.069	0.691	0.422	0.064		0.064	0.569

Data are presented as mean value ± SD. MetS: metabolic syndrome, BMI: body mass index, WC: waist circumference, SBP: systolic blood pressure, DBP: diastolic blood pressure, TG: triglyceride, TC: total cholesterol, LDL-C: low-density lipoprotein-cholesterol, HDL-C: high-density lipoprotein-cholesterol. The one-way ANOVA test was used. Two-tailed value ≤0.05 was considered statistically significant. ^aTT vs. GG value <0.05. ^bTG vs. GG value <0.05. ^cGT vs. TT value <0.05. ^dGG vs TT value <0.05.