Adiponectin Gene Polymorphisms and Possible Susceptibility to Metabolic Syndrome among the Sudanese Population: A Case-Control Study
Table 6
Haplotype frequencies in the MetS patients and the non-MetS group.
Linkage disequilibrium analysis of ADIPOQ SNPs
Haplotypes rs266729, rs2241766, and rs1501299
MetS patients frequency (%)
Non-MetS group frequency (%)
value
Odd ratio (95% CI: lower–upper)
CTG
136 (32.3%)
253 (60.2%)
<0.0001
0.316 (0.238–0.419)
CTT
139 (33.0%)
91 (21.6%)
<0.0001
1.788 (1.313–2.434)
CGG
54 (12.8%)
35 (8.3%)
0.033
1.622 (1.036–2.542)
GTG
56 (13.3%)
36 (8.5%)
0.027
1.641 (1.054–2.554)
CGT
17 (4.0%)
3 (0.7%)
0.001
5.863 (1.705–20.161)
GTT
11 (2.6%)
2 (0.4%)
0.011
5.621 (1.238–25.516)
OR: odd ratio, CI: confidence interval. The genetic analysis identifies a haplotype at the adiponectin locus. value ≤0.05 was considered statistically significant.