Research Article

Adiponectin Gene Polymorphisms and Possible Susceptibility to Metabolic Syndrome among the Sudanese Population: A Case-Control Study

Table 6

Haplotype frequencies in the MetS patients and the non-MetS group.


Linkage disequilibrium analysis of ADIPOQ SNPs
Haplotypes rs266729, rs2241766, and rs1501299MetS patients frequency (%)Non-MetS group frequency (%) valueOdd ratio (95% CI: lower–upper)

CTG136 (32.3%)253 (60.2%)<0.00010.316 (0.238–0.419)
CTT139 (33.0%)91 (21.6%)<0.00011.788 (1.313–2.434)
CGG54 (12.8%)35 (8.3%)0.0331.622 (1.036–2.542)
GTG56 (13.3%)36 (8.5%)0.0271.641 (1.054–2.554)
CGT17 (4.0%)3 (0.7%)0.0015.863 (1.705–20.161)
GTT11 (2.6%)2 (0.4%)0.0115.621 (1.238–25.516)

OR: odd ratio, CI: confidence interval. The genetic analysis identifies a haplotype at the adiponectin locus. value ≤0.05 was considered statistically significant.