Research Article

The Association between Visit-to-Visit Variability of Blood Pressure and the Risk of Metabolic Syndrome: The Moderating Effect of Weight

Table 2

Visit-to-visit variability of blood pressure and the risk of metabolic syndrome.

Visit-to-visit variability of blood pressureNo. of cases/totalModel 1aModel 2bModel 3c
OR (95% CIs)OR (95% CIs)OR (95% CIs)

SBP-SD
 Low (1st tertile, ≤6.55 mmHg)160/8651 (ref.)1 (ref.)1 (ref.)
 Middle (2nd tertile, 6.55–11.47 mmHg)188/8651.22 (0.97–1.55)1.25 (0.99–1.59)1.30 (1.01–1.69)
 High (3rd tertile, ≥11.47 mmHg)243/8641.72 (1.37–2.16)1.65 (1.30–2.09)1.70 (1.31–2.21)
DBP-SD
 Low (1st tertile, ≤4.33 mmHg)176/8651 (ref.)1 (ref.)1 (ref.)
 Middle (2nd tertile, 4.33–7.31 mmHg)201/8651.19 (0.94–1.48)1.15 (0.91–1.45)1.17 (0.91–1.52)
 High (3rd tertile, ≥7.31 mmHg)214/8641.29 (1.03–1.62)1.27 (1.01–1.60)1.41 (1.09–1.81)

OR, odds ratio; CIs, confidence intervals; VVV, visit-to-visit variability; SBP, systolic blood pressure; RMSE, root mean square error; SD, standard division; DBP, diastolic blood pressure; aModel 1: unadjusted. bModel 2: adjusted for age, gender, and baseline systolic blood pressure and diastolic blood pressure. cModel 3: Model 2 plus smoking, drinking, baseline value of waist circumference, blood urea nitrogen, fasting plasma glucose, HbA1c, total cholesterol, triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, creatinine, uric acid, C-reactive protein, and use of antihypertensive, lipid-lowering, and antidiabetic drugs.