Risk Factors for Granulocytopenia in Patients with Graves’ Disease Receiving Antithyroid Drugs

Table 2

Multivariate logistic regression analysis for granulocytopenia induced by antithyroid drugs.

Factors	β	S.E.	Wald	OR (95% CI)
Gender
Male				1.000
Female	0.826	0.314	6.918	2.285 (1.234, 4.229)	0.009
ALT (IU/L)
<40				1.000
≥40	1.158	0.321	13.023	3.183 (1.697, 5.968)	<0.001
WBC (×10^9/L)
<4				1.000
4–10	−2.068	0.369	31.459	0.126 (0.061, 0.26)	<0.001
>10	−2.266	0.842	7.244	0.104 (0.02, 0.54)	0.007
NLR
<1				1.000
1–3	−3.3	0.312	111.69	0.037 (0.02, 0.068)	<0.001
>3	−21.765	2874.561	0	0 (0.000)	0.994
Constant	1.515	0.471	10.363	4.549	0.001

ALT: alanine aminotransferase, WBC: white blood cell counts, and NLR: neutrophil-to-lymphocyte ratio.