International Journal of Endocrinology

Islets and Glucose Homeostasis


Status
Published

Lead Editor

1Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan

2Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong

3Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung University and Chang Gung Memorial Hospital, Taoyuan, Taiwan


Islets and Glucose Homeostasis

Description

Diabetes is caused by relative insulin deficiency resulting in the inability to regulate blood glucose. This can occur because of loss of endogenous insulin through autoimmune depletion of pancreatic beta cells (type 1 diabetes). Alternatively, the disease may manifest as insulin resistance with eventual beta cell failure and apoptosis arising, in part, from increased metabolic and secretory demands (type 2 diabetes). Regardless of the underlying cause of the disease, insufficient beta cell mass leads to dependence on exogenous insulin for blood glucose regulation. The morbidities associated with diabetes are significant. The knowledge about islet cell development, cell-based therapy, pancreas transplantation, and factors attributing to changing the secretory function and/or mass of islet beta cells might help to develop a novel treatment to diabetes.

We invite investigators to contribute original research articles as well as review articles that explore aspects in islet developmental biology, islet or whole pancreas transplantation, cell-based therapy, apoptotic and antiapoptotic signals of islet beta cells, and therapeutic strategies to improve either beta cell function or beta cell mass. Potential topics include, but are not limited to:

  • Islet developmental biology
  • Islet or whole pancreas transplantation
  • Generate a beta-like cells from pancreatic progenitor cells
  • Generate a beta-like cells from transdifferentiation of nonbeta cells
  • Apoptotic and antiapoptotic signals of islet beta cells
  • Therapeutic strategies to improve insulin secretory function of islet beta cells
  • Therapeutic strategies to increase beta cell mass

Before submission authors should carefully read over the journal’s Author Guidelines which are located at http://www.hindawi.com/journals/ije/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/ije/islets/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 358460
  • - Editorial

Islets and Glucose Homeostasis

Tien-Jyun Chang | Gang Xu | Jyuhn-Huarng Juang
  • Special Issue
  • - Volume 2015
  • - Article ID 675245
  • - Research Article

The Estimation of First-Phase Insulin Secretion by Using Components of the Metabolic Syndrome in a Chinese Population

Jiunn-diann Lin | Chun-Hsien Hsu | ... | Yen-Lin Chen
  • Special Issue
  • - Volume 2014
  • - Article ID 983016
  • - Research Article

Genetic Variations in the Kir6.2 Subunit (KCNJ11) of Pancreatic ATP-Sensitive Potassium Channel Gene Are Associated with Insulin Response to Glucose Loading and Early Onset of Type 2 Diabetes in Childhood and Adolescence in Taiwan

Yi-Der Jiang | Lee-Ming Chuang | ... | Tien-Jyun Chang
  • Special Issue
  • - Volume 2014
  • - Article ID 983453
  • - Research Article

Augmented β-Cell Function and Mass in Glucocorticoid-Treated Rodents Are Associated with Increased Islet Ir-β/AKT/mTOR and Decreased AMPK/ACC and AS160 Signaling

André O. P. Protzek | José M. Costa-Júnior | ... | Antonio C. Boschero
  • Special Issue
  • - Volume 2014
  • - Article ID 795283
  • - Research Article

Effects of Dipeptidyl Peptidase-4 Inhibition with MK-0431 on Syngeneic Mouse Islet Transplantation

Jyuhn-Huarng Juang | Chien-Hung Kuo | ... | Chiung-Tong Chen
  • Special Issue
  • - Volume 2014
  • - Article ID 435481
  • - Research Article

Prevention and Reversal of Diabetes by All-Trans Retinoid Acid and Exendin-4 in NOD Mice

Jyuhn-Huarng Juang | Yang-Hau Van | ... | Han-Ying Chang
  • Special Issue
  • - Volume 2014
  • - Article ID 451035
  • - Review Article

Inflammatory Response in Islet Transplantation

Mazhar A. Kanak | Morihito Takita | ... | Bashoo Naziruddin
International Journal of Endocrinology
 Journal metrics
Acceptance rate30%
Submission to final decision70 days
Acceptance to publication40 days
CiteScore2.350
Impact Factor2.287
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