International Journal of Endocrinology

Fat, Muscle, and Bone Interactions in Obesity and the Metabolic Syndrome


Publishing date
21 Feb 2014
Status
Published
Submission deadline
04 Oct 2013

1Division of Endocrinology, University of New Mexico/New Mexico VA Health Care System, Albuquerque, NM, USA

2Division of Geriatrics and Palliative Care Medicine, University of New Mexico/New Mexico VA Health Care System, Albuquerque, NM, USA

3Department of Medicine, Campus Biomedico, Rome, Italy

4Department of Preventive Medicine, University of Otago, Dunedin, New Zealand


Fat, Muscle, and Bone Interactions in Obesity and the Metabolic Syndrome

Description

There is growing interest in the interactions between fat, muscle, and bone in the context of obesity/metabolic syndrome. Fatty infiltration in the muscles associated with obesity/metabolic syndrome leads to poor muscle quality, poor strength, and poor physical function most especially in the elderly. In addition, adipose tissue secretes inflammatory cytokines that may result in skeletal muscle inflammation and poor bone quality. In fact, for bone, the traditional concept that a high body weight is osteoprotective is now challenged by recent findings of an increased prevalence of fractures as BMI goes from overweight to obese. Recent scientific advances have shown that cell signals that promote mesenchymal stem cells to differentiate into the adipogenic pathway are associated with suppression of signaling in the myogenic and osteogenic pathways and vice versa. Knowledge and understanding of these interactions have led to the development of animal models, identification of novel targets, and the development of modalities that may alleviate the negative consequences of obesity/metabolic syndrome on the musculoskeletal system aside from improving the associated metabolic derangement.

We invite investigators to contribute original research articles as well as review articles that will promote the continuing interest in understanding the underlying mechanisms of fat, muscle, and bone interactions in obesity and the development of strategies to minimize or treat muscle and bone dysfunction that accompanies obesity/metabolic dysfunction. We are particularly interested in articles reporting or describing research on topics which include, but are not limited to:

  • Pathways involved in fat redistribution associated with obesity/metabolic syndrome
  • Role of inflammation in muscle and bone dysfunction in obesity
  • Evaluation and characterization of muscle dysfunction/sarcopenia in obesity
  • Evaluation of bone quantity and bone quality in obesity
  • Bone marrow characterization/analysis in animal or human models of obesity
  • Role of lifestyle therapy in the prevention or reversal of muscle dysfunction/sacropenia associated with obesity
  • Role of lifestyle therapy in the prevention or reversal of deterioration in bone quality associated with obesity
  • Drug therapies that may improve muscle or bone metabolism in addition to improving the metabolic dysfunction in obesity/metabolic syndrome

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/ije/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/ije/fmb/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2014
  • - Article ID 247076
  • - Editorial

Fat, Muscle, and Bone Interactions in Obesity and the Metabolic Syndrome

Reina Armamento-Villareal | Nicola Napoli | ... | Dennis Villareal
  • Special Issue
  • - Volume 2014
  • - Article ID 670262
  • - Review Article

Obesity as a Risk Factor for Tendinopathy: A Systematic Review

Francesco Franceschi | Rocco Papalia | ... | Vincenzo Denaro
  • Special Issue
  • - Volume 2014
  • - Article ID 841248
  • - Review Article

Vitamin D and Its Relationship with Obesity and Muscle

Cristiana Cipriani | Jessica Pepe | ... | Salvatore Minisola
  • Special Issue
  • - Volume 2014
  • - Article ID 690783
  • - Review Article

The Alliance of Mesenchymal Stem Cells, Bone, and Diabetes

Nicola Napoli | Rocky Strollo | ... | Sol Epstein
  • Special Issue
  • - Volume 2014
  • - Article ID 487463
  • - Clinical Study

Serum 25-OH Vitamin D in relation to Bone Mineral Density and Bone Turnover

Nicola Napoli | Rocky Strollo | ... | Enrico Carmina
  • Special Issue
  • - Volume 2014
  • - Article ID 507395
  • - Research Article

Testosterone and Adipokines are Determinants of Physical Performance, Strength, and Aerobic Fitness in Frail, Obese, Older Adults

Lina E. Aguirre | Irum Zeb Jan | ... | Reina Armamento-Villareal
  • Special Issue
  • - Volume 2014
  • - Article ID 372021
  • - Clinical Study

Hip Osteoarthritis and Osteoporosis: Clinical and Histomorphometric Considerations

Umberto Tarantino | Monica Celi | ... | Augusto Orlandi
  • Special Issue
  • - Volume 2014
  • - Article ID 685820
  • - Clinical Study

Role of Serum Fibrinogen Levels in Patients with Rotator Cuff Tears

Umile Giuseppe Longo | Stefano Petrillo | ... | Vincenzo Denaro
  • Special Issue
  • - Volume 2014
  • - Article ID 902186
  • - Research Article

Irisin Enhances Osteoblast Differentiation In Vitro

Graziana Colaianni | Concetta Cuscito | ... | Maria Grano
  • Special Issue
  • - Volume 2014
  • - Article ID 586017
  • - Research Article

Mitochondrial DNA Copy Number in Peripheral Blood Is Independently Associated with Visceral Fat Accumulation in Healthy Young Adults

Jee-Yon Lee | Duk-Chul Lee | ... | Ji-Won Lee
International Journal of Endocrinology
 Journal metrics
Acceptance rate35%
Submission to final decision48 days
Acceptance to publication46 days
CiteScore3.500
Impact Factor2.299
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