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International Journal of Electrochemistry
Volume 2011 (2011), Article ID 502364, 6 pages
Research Article

Chiral Discrimination of Tryptophan Enantiomers via (1R, 2R)-2-Amino-1, 2-Diphenyl Ethanol Modified Interface

Key Laboratory on Luminescence and Real-Time Analysis of Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China

Received 5 May 2011; Accepted 18 June 2011

Academic Editor: Valentin Mirceski

Copyright © 2011 Juan Zhou et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The paper reported that a simple chiral selective interface constructed by (1R, 2R)-2-amino-1, 2-diphenyl ethanol had been developed to discriminate tryptophan enantiomers. Cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) were used for the characteristic analysis of the electrode. The results indicated that the interface showed stable and sensitive property to determine the tryptophan enantiomers. Moreover, it exhibited the better stereoselectivity for L-tryptophan than that for D-tryptophan. The discrimination characteristics of the chiral selective interface for discriminating tryptophan enantiomers, including the response time, the effect of tryptophan enantiomers concentration, and the stability, were investigated in detail. In addition, the chiral selective interface was used to determine the enantiomeric composition of L- and D-tryptophan enantiomer mixtures by measuring the relative change of the peak current as well as in pure enantiomeric solutions. These results suggested that the chiral selective interface has the potential for enantiomeric discrimination of tryptophan enantiomers.