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International Journal of Electrochemistry
Volume 2013, Article ID 803672, 10 pages
http://dx.doi.org/10.1155/2013/803672
Research Article

A Dopamine Sensor Based on Pre-Concentration by Magnetic Nanoparticles

1Material Research School, NSTRI, Isfahan 81465-1589, Iran
2Islamic Azad University, Shahreza Branch, Shahreza 86145-311, Iran

Received 30 April 2013; Revised 11 August 2013; Accepted 20 August 2013

Academic Editor: Shen-Ming Chen

Copyright © 2013 Mojtaba Bagherzadeh et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Herein, Fe3O4 magnetic nanoparticles (MNPs) were synthesized and characterized. Afterward, a magnetic carbon paste electrode (MCPE) was modified with MNPs via casting and drying MNPs on top of the MCPE (MCPE/MNP). Electrochemical behavior of the MCPE/MNP was studied by cyclic voltammetry in the presence of [Fe(CN)6]3−/4− as a redox probe, and surface of MNPs was evaluated as . The behavior of MCPE/MNP towards dopamine (DA) and ascorbic acid (AA) has been investigated by electrochemical methods, and the obtained results showed that the MCPE/MNP has adsorption behavior towards only DA. Based on this behavior, the DA molecules were pre-concentrated on top of the MCPE/MNP and followed with stripping in DA free solution. Subsequent to experimental and instrumental optimization, a calibration curve from to  M DA with , DL =  M DA, and RSD = 4.6%, was obtained in the presence of  M AA. Performance of the MCPE/MNP was successfully tested in a pharmaceutical sample.