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International Journal of Electrochemistry
Volume 2013 (2013), Article ID 902872, 8 pages
Research Article

Voltammetry Study of an Anti-HIV Compound by means of a Thin Organic Membrane

1Laboratoire de Chimie Analytique, Faculté des Sciences, Université de Yaoundé 1, BP 812, Yaoundé, Cameroon
2Laboratoire de Chimie Minérale, Faculté des Sciences, Université de Douala, BP 24157, Douala, Cameroon

Received 20 June 2013; Revised 17 August 2013; Accepted 20 August 2013

Academic Editor: Angela Molina

Copyright © 2013 Achille Nassi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Cyclic and square wave voltammetries have been used to study electrochemical behaviour of an anti-HIV agent (Guttiferone A) at the liquid-liquid interface. The thin organic membrane is formed by an organic solvent containing redox probe. Guttiferone A, a benzophenone (BP) with appropriate electrolyte. It is demonstrated that BP possesses three reduction systems due to the redox transformation of the three tautomeric forms that lead to the migration of proton between the hydroxyl group in position 4 and the carbonyl group in positions 2 and 10. The transfer of proton from the aqueous solution to the organic phase is crucial for the redox transformation of BP into the organic membrane. The voltammograms obtained are strongly influenced by the pH of the aqueous phase. The electrochemical mechanism consists of 2e/2H+ exchange to form the separate redox compound BPH2.