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Yeast
Volume 1 (2000), Issue 3, Pages 218-224
http://dx.doi.org/10.1002/1097-0061(20000930)17:3<218::AID-YEA37>3.0.CO;2-X
Review Article

The Gene Guessing Game

The Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK

Copyright © 2000 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

A recent flurry of publications and media attention has revived interest in the question of how many genes exist in the human genome. Here, I review the estimates and use genomic sequence data from human chromosomes 21 and 22 to establish my own prediction.