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Comparative and Functional Genomics
Volume 4, Issue 4, Pages 424-427
http://dx.doi.org/10.1002/cfg.313
Conference review

Multiple Sequence Alignments as Tools for Protein Structure and Function Prediction

Protein Design Group, National Centre for Biotechnology, CNB-CSIC, Madrid, Spain

Received 22 May 2003; Revised 6 June 2003; Accepted 6 June 2003

Copyright © 2003 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Multiple sequence alignments have much to offer to the understanding of protein structure, evolution and function. We are developing approaches to use this information in predicting protein-binding specificity, intra-protein and protein-protein interactions, and in reconstructing protein interaction networks.