Effects of Subminimum Inhibitory Concentrations of Antibiotics on the Pasteurella multocida Proteome: A Systems Approach

Table 1

Significantly overrepresented GO groups in response to sub-MIC AMX, CTC and ENR.

GO ID	Name
GO:0009257	10-formyltetrahydrofolate biosynthesis
GO:0045733	Acetate catabolism
GO:0006086	Acetyl-CoA biosynthesis from pyruvate
GO:0006418	Amino acid activation
GO:0009063	Amino acid catabolism
GO:0046349	Amino sugar biosynthesis
GO:0009061	Anaerobic respiration
GO:0015986	ATP synthesis coupled proton transport
GO:0030113	Capsule (sensu Bacteria)
GO:0016052	Carbohydrate catabolism
GO:0042280	Cell surface antigen activity, host-interacting
GO:0017004	Cytochrome biogenesis
GO:0005737	Cytoplasm
GO:0009281	Cytosolic ribosome (sensu Bacteria)
GO:0006308	DNA catabolism
GO:0006261	DNA dependent DNA replication
GO:0006310	DNA recombination
GO:0006113	Fermentation
GO:0006012	Galactose metabolism
GO:0006094	Gluconeogenesis
GO:0006096	Glycolysis
GO:0009436	Glyoxylate catabolism
GO:0009089	Lysine biosynthesis via diaminopimelate
GO:0009086	Methionine biosynthesis
GO:0006777	Mo-molybdopterin cofactor biosynthesis
GO:0015949	Nucleobase, nucleoside and nucleotide interconversion
GO:0009052	Pentose-phosphate shunt, non-oxidative branch
GO:0009051	Pentose-phosphate shunt, oxidative branch
GO:0008233	Peptidase activity
GO:0009252	Peptidoglycan biosynthesis
GO:0000270	Peptidoglycan metabolism
GO:0042597	Periplasmic space
GO:0006412	Protein biosynthesis
GO:0006457	Protein folding
GO:0006508	Proteolysis and peptidolysis
GO:0006164	Purine nucleotide biosynthesis
GO:0009152	Purine ribonucleotide biosynthesis
GO:0042867	Pyruvate catabolism
GO:0009269	Response to dessication
GO:0006401	RNA catabolism
GO:0009451	RNA modification
GO:0003735	Structural constituent of ribosome
GO:0009088	Threonine biosynthesis
GO:0006350	Transcription
GO:0009386	Translational attenuation
GO:0006099	Tricarboxylic acid cycle

AMX: amoxicillin; CTC: chlortetracycline; ENR: enrofloxacin.