Research Article

Global Transcriptional Analysis of Yeast Cell Death Induced by Mutation of Sister Chromatid Cohesin

Table 7

List of differentially regulated genes that are related to cell cycle in time point 2 (note that all genes are upregulated).

Gene nameFold changeDescription
mcd1-1pds5-1

CSM425.9913.0013.93Meiotic chromosome segregation
REC810.1014.908.60Meiotic sister chromatid cohesion
SPR318.3818.3813.00Cellular morphogenesis during conjugation with cellular fusion
REC11417.154.9222.63Meiotic recombination
MER117.152.8318.38Regulation of nuclear mRNA splicing
CST913.934.0014.93Synaptonemal complex formation
SWI413.933.739.19G1/S transition of mitotic cell cycle
SPS413.004.597.46DNA metabolism
OKP113.002.148.57Chromosome segregation
SFI112.133.7311.31G2/M transition of mitotic cell cycle
EPL112.133.738.57Regulation of transcription from RNA polymerase II promoter
MPS312.132.8310.56Nuclear migration during conjugation with cellular fusion
SCC412.132.309.19Double-strand break repair
MAD212.132.0011.31Mitotic spindle checkpoint
FKH211.313.4813.00G2/M-specific transcription in mitotic cell cycle
ISC1011.312.6414.93Protein required for sporulation
MPC5410.5621.1117.15Spore wall assembly
DMA210.564.299.85Establishment of mitotic spindle orientation
REC10710.563.259.85Meiotic recombination
IBD210.563.0317.15Mitotic spindle checkpoint
MPT510.562.6412.13Reentry into mitotic cell cycle after pheromone arrest
MAD310.562.649.85Mitotic spindle checkpoint
CLN310.562.309.85G1 cyclin involved in cell cycle progression
REC1049.8514.939.85Meiotic recombination
KEL29.855.667.46Regulation of exit from mitosis
KAR39.854.9210.56Mitotic sister chromatid cohesion
BCK29.853.259.19Regulation of progression through cell cycle
RTT1019.852.839.85Negative regulation of DNA transposition
SLK199.852.467.46Meiosis/mitotic spindle organization
LRS49.852.3010.56Protein involved in rDNA silencing
MND19.1968.596.96Meiotic recombination
HOP29.194.9214.93Meiotic recombination
KIP19.193.037.46Mitotic spindle assembly and chromosome segregation
SLD29.192.469.19DNA strand elongation
TFB39.192.149.19Regulation of transcription
TAF29.192.149.19G1-specific transcription in mitotic cell cycle
SPO118.577.468.57DNA metabolism
PRP468.573.7311.31Nuclear mRNA splicing
UME68.573.259.85G2/M transition of mitotic cell cycle
ELG18.572.4612.13Regulation of DNA transposition
CDC458.572.469.19Prereplicative complex formation and maintenance
BIR18.572.468.57Mitotic spindle elongation
CHL18.572.468.00Mitotic sister chromatid cohesion
SGO18.572.308.57Sister chromatid segregation
SLD38.572.149.19DNA unwinding during replication
CEF18.003.7310.56Nuclear mRNA splicing
MPS18.003.258.57Mitotic spindle assembly
SET38.003.257.46Histone deacetylation
SPC728.002.648.00Mitotic spindle elongation
CDC268.002.4618.38Protein ubiquitination
MCM228.002.309.85Chromosome segregation
MMS48.002.008.00Involvement in recombination and DNA repair
NIP1007.464.929.85Establishment of mitotic spindle orientation
DBF47.463.259.19Regulation of DNA replication
MEC37.462.836.96DNA damage checkpoint
PIN47.462.469.19G2/M transition of mitotic cell cycle
GIC27.462.149.19Regulation of exit from mitosis
IME16.9617.1516.00Regulation of transcription
LCD16.963.487.46DNA damage checkpoint
ULP16.962.467.46Ubl (ubiquitin-like protein)-specific protease
YOR019W13.938.5711.31Protein of unknown function
SPR610.562.309.19Protein of unknown function